Dr. Godsey earned his PhD in 2001 from the Department of Biochemistry and Molecular Biology at Oregon Health & Science University working the laboratory of Richard Brennan solving the structures of proteins involved in bacterial multidrug resistance using X-ray crystallography. His postdoctoral work at the University of Illinois in Chicago with Arnon Lavie explored the structural biology of cancer prodrug metabolism. In 2005, he accepted a position on the faculty of Concordia University in Portland, Oregon, where he ran a small student-centered laboratory and taught classes ranging from introductory chemistry to senior-level biochemistry and physical chemistry. He spent summer and sabbaticals doing research in labs at Yale, Northwestern, and OHSU. Dr. Godsey was promoted to Professor and co-chair of his department before the closure of the university in 2020. Before joining the Department of Biochemistry at the University of Vermont in 2022, he used single-particle cryogenic electron microscopy to solve the structures of membrane proteins in complexes with small-molecule inhibitors.
CU Faculty Development Grants and Scholarship Recipient (2010-2007)
Concordia Faculty Research Grants (2007, 2009, 2010, 2011)
National Institutes of Health Post-doctoral Training Grant, Physiology & Biophysics, UIC, 2004-2005
American Crystallographic Association Travel Grant, 2002
Best Student Presentation, Graduate Student Organization Student Research Forum, 2001
National Institutes of Health Pre-doctoral Training Grant, Molecular & Medical Genetics, OHSU, 1999-2001
N. L. Tartar Research Fellowship, 1999
Oken, A. C., Krishnamurthy, I., Savage, J. C., Lisi, N. E., Godsey, M. H., & Mansoor, S. E. (2022). Molecular pharmacology of P2X receptors: Exploring druggable domains revealed by structural biology. Front. Pharmacol., 13, 925880.
Godsey, M. H., Davulcu, O., Nix, J. C., Skalicky, J. J., Brüschweiler, R. P., & Chapman, M. S. (2016). The sampling of conformational dynamics in ambient-temperature crystal structures of arginine kinase. Structure, 24(10), 1658–1667.
Godsey, M. H., Minasov, G., Shuvalova Ludmilla and Brunzelle, J. S., Vorontsov, I. I., Collart, F. R., & Anderson, W. F. (2007). The 2.2 Å resolution crystal structure ofBacillus cereusNif3-family protein YqfO reveals a conserved dimetal-binding motif and a regulatory domain. Protein Sci., 16(7), 1285–1293.
Godsey, M. H., Ort, S., Sabini, E., Konrad, M., & Lavie, A. (2006). Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization. Biochemistry, 45(2), 452–461.
Godsey, M. H., Zheleznova Heldwein, E. E., & Brennan, R. G. (2002). Structural biology of bacterial multidrug resistance gene regulators. J. Biol. Chem., 277(43), 40169–40172.
Godsey, M. H., Baranova, N. N., Neyfakh, A. A., & Brennan, R. G. (2001). Crystal structure of MtaN, a global multidrug transporter gene activator. J. Biol. Chem., 276(50), 47178–47184.
Godsey, M. H., Baranova, N. N., Neyfakh, A. A., & Brennan, R. G. (2000). Crystallization and preliminary X-ray diffraction studies on the DNA-binding domain of the multidrug transporter activation protein (MtaN) from Bacillus subtilis. Acta Crystallogr. D Biol. Crystallogr., 56(Pt 11), 1456–1458.