Gregory L Holmes, M.D.

Gregory L Holmes, M.D.

Dr. Holmes, Professor and Chair of the Department of Neurological Sciences, is a pediatric neurologist who has both clinical and research interests in childhood epilepsy. He is widely published as a researcher focusing on the delineation, effects and treatment of pediatric/developmental epilepsy. In addition to being active in professional society and hospital committees, he has served on the editorial boards of 10 epilepsy and neurology journals and has been on multiple NIH study sections. Dr. Holmes has also reviewed grants from around the world including Canada, Israel, Australia, France, the UK and Belgium. He is the past president of the American Epilepsy Society and has received many honors including the American Epilepsy Society Research Award, Basic Science Award (1989), Pierre Gloor Research Award, American Clinical Neurophysiology Society (2001), Hoyer Lecturer, National Institutes of Health (2009) and Sachs Lecturer, Child Neurology Society (2009). Dr. Holmes is also the chief physician for Camp Wee Kan Tu, a camp for children with epilepsy. Developing therapy to prevent epilepsy has been a lifelong goal. Dr. Holmes is a PEMM faculty member, and is always interested in hearing from potential Graduate Student Applicants.

Contact Information
E-mail: gregory.holmes@med.uvm.edu
Office Location: 95 Carrigan Drive, Stafford 118C, Burlington, VT 05405

Education

1996 MA (Honorary), Harvard University, Cambridge, Massachusetts

1974 MD, University of Virginia School of Medicine, Charlottesville, Virginia

1970 BS, Washington and Lee University, Lexington, Virginia

Academic Appointments

2013-present Professor and Chair, Department of Neurological Sciences, University of Vermont, Burlington, Vermont

2002-2013 Professor of Neurology and Pediatrics, Dartmouth Medical School, Hanover, New Hampshire

1996-2002 Professor of Neurology, Harvard Medical School

1988-1996 Associate Professor of Neurology, Harvard Medical School

1986-1988 Associate Professor of Neurology and Pediatrics, Medical College of Georgia

1986 Associate Professor of Neurology and Pediatrics, University of Connecticut Health Center

1979-1986 Assistant Professor of Neurology and Pediatrics, University of Connecticut Health Center

Awards and Honors

Academic Awards

1981  Sidney Farber Research Award, United Cerebral Palsy Association, Inc

1986  The John Horsley Memorial Prize, University of Virginia, School of Medicine

1989  Michael Prize awarded by Stiftung Michael, Bonn, Germany. Basic Scientist Award for outstanding work in the field of epilepsy research by a young investigator

1989  Milken Family Medical Foundation - American Epilepsy Society Research Award. Basic Scientist Award for outstanding work in the field of epilepsy research

1990  Pierre Gloor Award for outstanding achievements in research. American Clinical  Neurophysiology Society

1991  Segawa Award, Tokyo, Japan

2007  Ambassador for Epilepsy, International League Against Epilepsy

2011  Dartmouth College Arts & Sciences Graduate Faculty Mentor Award

Lay Awards

Fellow Awards

Student Awards

Teaching Awards

Publications (Peer Reviewed)

Most recent (selected from 390). To view more of Dr. Holmes publications, please visit PubMed.

1.   Hernan AE, Barry JM, Scott RC, Holmes GL. The effect of focal inerictal spikes during development on short-term synaptic plasticity in the prefrontal cortex. Poster presentation at American Epilepsy Society Meeting. (Abst. 3.039), 2012.

2.   Bender AC, Luikart B, Holmes GL, Scott RC, Lenck-Santini PP. Rnai-mediated knockdown of nav1.1 disrupts a cognitive neural network. Poster presentation at American Epilepsy Society Meeting. (Abst. 2.013),2012.

3.   Titiz AS, Holmes GL, Scott RC, Lenck-Santini PP. From rats to men: a virtual water-maze task shows cognitive impairments in patients with epilepsy. Poster presentation at American Epilepsy Society Meeting. (Abst. 3.045),2012.

4.   Kleen J, Lenck-Santini PP, Scott RC, Holmes GL, Jobst B. Transient cognitive impairment due hippocampal interictal epileptiform activity in humans. Poster presentation at American Epilepsy Society Meeting. (Abst. 2.300),2012.

5.   Hartshorn AL, Guardia CF, Thadani VM, Holmes GL, Jobst BC. Late onset Rasmussen's encephalitis: a report of 4 cases. Poster presentation at American Epilepsy Society Meeting. (Abst. 3.126),2012.

6.   Titiz, AS, Scott RC, Holmes GL, Lenck-Santini PP. The firing properties and replay of hippocampal place cells in rats with epilepsy during sleep. Poster presentation at Society for Neuroscience (447.08/H13).2012.

7.   Jenks KR, Lucas MM, Robbins A, Holmes GL, Barry JM, Scott RC. Environmental enrichment improves spatial learning in animals with a brain malformation. Poster presentation at Society for Neuroscience (447.07/H12).2012.

8.   Bender A, Holmes GL, Scott RC, Lenck-Santini PP. Characterization of Nav1.1 in the medial septum and diagonal band of Broca: Implications for cognitive deficits in Dravet syndrome and Alzheimer's disease. Poster presentation at Society for Neuroscience (447.07/H12).2012.

9.   Koshbin S, Herring A, Holmes GL, Schomer D, Hoch D, Dooling EC, Vining Ep, Holmes LB. Inter-rater agreement for diagnoses of epilepsy in pregnant women. Epilepsy & Behavior. 2013 Feb 14;27(1):148-153. PMID:23416992

10. Bender AC, Natola H, Ndong C, Holmes GL, Scott RC, Lenck-Santini PP. Focal Scn1a knockdown induces cognitive impairment without seizures. Neurobiology of Disease. 2013 Jan 11. [Epub ahead of print]