Education

1992     Fellowship - Columbia University, Molecular Genetics
1990     Fellowship - Columbia University, Clinical Genetics
1988     Residency - University of Chicago, Chicago, IL
1984     M.D. -  University of Chicago, Chicago, IL
1980     B.A. - University of Chicago, Chicago, IL, Medicine

Research Interests

For the past several years, research in Dr. Brown’s laboratory has been focused on understanding the molecular and epigenetic basis of maternal vascular adaptation to pregnancy.  Prior research interests have included studies on the molecular basis of the brain malformation known as holoprosencephaly as well as the development of a method for non-invasive detection of fetal chromosome abnormalities.

Expertise

Prenatal Diagnosis
Reproductive Genetics

Publications

Cooper K. and Brown S.  ACTA2 mutation and postpartum hemorrhage, a case report.  BMC Medical Genetics 2017 Dec 4;18(1):143

Akoury E, Gupta N, Bagga R, Brown S, Déry C, Kabra M, Srinivasan R, Slim R. Live births in women with recurrent hydatidiform mole and two NLRP7 mutations.  Reprod Biomed Online. 2015 Jul;31(1):120-4.

Bonney EA, Brown SA.  To drive or be driven: the path of a mouse model of recurrent pregnancy loss; Reproduction Reproduction. 2014 Apr 8;147(5):R153-67.

Jones D, Fiozzo F, Waters B, McKnight D, Brown S  First-trimester diagnosis of Meckel-Gruber Syndrome by fetal ultrasound with molecular identification of CC2D2A muations by next-generation sequencing.  Ultrasound Obstet Gynecol. 2014 Dec;44(6):719-21

Kline JK, Kinney AM, Levin B, Brown SA, Hadd AG, Warburton D.  Intermediate CGG repeat length at the FMR1 locus is not associated with hormonal indicators of ovarian aging. Menopause. 2014 2014 Jul;21(7):740-8

Brown LY, Bonney EA, Raj RS, Nielsen B, Brown S.  Global disturbance of DNA methylation in the uterine decidua in the CBA/J x DBA/2 mouse model of pregnancy failure; Biol Reprod. 2013 Nov 21;89(5):120.

Brown L, Mount  S, Reddy R, Slim R, Wong C, Jobanputra V, Clifford P, Merrill L, Brown S.   Pregnancy loss in a woman with NLRP7 mutation:  Not all molar pregnancies can be easily classified as either "partial" or "complete" hydatidiform moles Int J Gynecol Pathol. 2013 Jul;32(4):399-405. 

See PubMed listing here.