Jonathan E. Boyson, PhD

Jonathan E. Boyson, PhD

Professor
Division Chief, Surgical Research

Roger G. Allbee  '31 Professorship in Surgery

Cancer Center Member

Contact Information
E-mail: jboyson@uvm.edu
Phone:
802-656-8846
Office Location:
Given D319-D, 89 Beaumont Ave., Burlington, VT 05405

Education

PhD, University of Wisconsin at Madison, Madison, WI (1997)
BS, University of Vermont, Burlington, VT (1989)

Postdoctoral Training

Post-doctoral Fellow, Molecular and Cellular Biology, Harvard University, Cambridge, MA (2003)
Post-doctoral Fellow, Wisconsin Regional Primate Research Center, University of Wisconsin – Madison, Madison, WI  (1998)

Academic Appointments

Professor, Division of Surgical Research, Department of Surgery, The Larner College of Medicine, University of Vermont, Burlington, VT (2023-Present)

 Associate Professor, Division of Surgical Research, Department of Surgery, The Larner College of Medicine, University of Vermont, Burlington, VT (2009-2023)

Vice Chair of Research, Division of Surgical Research, Department of Surgery, The Larner College of Medicine, University of Vermont, Burlington, VT (2011-2019)

Director, Flow Cytometry and Cell Sorting Facility, The Larner College of Medicine, University of Vermont, Burlington, VT (2011-2019)

Interim Vice Chair, Director of Surgical Research, Division of Surgical Research, Department of Surgery, College of Medicine, University of Vermont, Burlington, VT (2008-2011)

Affiliate Member, Vermont Cancer Center, College of Medicine, University of Vermont, Burlington, VT (2003-2013)

Assistant Professor, Division of Transplantation Surgery and Immunology, Department of Surgery, College of Medicine, University of Vermont, Burlington, VT (2003-2009)

Other Professional Appointments

Research Associate, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA (2002-2003)

Awards and Honors

The Roger H. Allbee '31 Professorship in Surgery

James E. Demeules Surgical Research Award (2006) 
New Research Initiative Award (2006)
National Research Service Award (1998)

Publications

Rapid Induction and Maintenance of Virus-Specific CD8+ TERMA and CD+ TEM Cells Following Protective Vaccination Against Dengue Virus Challenge in Humans.
Graham N. Eisenhauer P, Diehl SA, Pierce KK, Whitehead SS, Durbin AP, Kirkpatrick BD, Sette A, Weiskopf D, Boyson JE, Botten JW. Front Immunol. 2020 Mar 24;11:479. doi: 10.3389/fimmu.2020.00479. eCollection 2020.PMID: 32265929

Critical Role for SLAM/SAP Signaling in the Thymic Developmental Programming of IL-17- and IFN-?-Producing ?d T Cells.
Diez O, DeVault VL, Musial SC, Mistri SK, Mei L, Baraev A, Dragon JA, Krementsov D, Veillette A, Boyson JE. Immunol. 2020 Mar 15;204(6):1521-1534. doi: 10.4049/jimmunol.1901082. Epub 2020 Feb 5.PMID: 32024701

Serum Amyloid A3 is Required for Normal Lung Development and Survival Following Influenza Infection.
Ather JL, Dienz O, Boyson JE, Anathy V, Amiel E, Poynter ME. Sci Rep. 2018 Nov 8;8(1):16571. doi: 10.1038/s41598-018-34901-x.PMID: 30410021

Bacterial Lipoproteins Constitute the TLR2-Stimulating Activity of Serum Amyloid A.
Burgess EJ, Hoyt LR, Randall MJ, Mank MM, Bivona JJ 3rd, Eisenhauer PL, Botten JW, Ballif BA, Lam TW, Wargo MJ, Boyson JE, Ather JL, Poynter ME. J Immunol. 2018 Oct 15;201(8):2377-2384. doi: 10.4049/jimmunol.1800503. Epub 2018 Aug 29. PMID: 30158125

Regulation of Invariant NKT Cell Development and Function by a 0.14 Mbp Locus on Chromosome 1: A Possible Role For Fcgr3. 
DeVailt VL, Malagic M, Mei L, Dienz O, Lilley GWJ, Benoit P, Mistri SK, Musial SC, Ather JL, Poynter ME, Boyson JE. Genes Immun. 2019 Apr;20(4):261-272. doi: 10.1038/s41435-018-0031-2. Epub 2018 Jun 8.PMID: 29880961

DeVault, V.L., Malagic, M., Mei, L., Dienz, O., Lilley, G.W.J., Benoit, P., Mistri, S.K., Musial, S.C., Ather, J.L., Poynter, M.E., and J.E. Boyson. Regulation of invariant iNKT cell development and function by a 0.1 Mbp locus on chromosome 1: a possible role for Fcgr3. Genes and Immunity (in press).

Genetic variation in chromosome Y regulates susceptibility to influenza A virus infection.
Krementsov DN, Case LK, Dienz O, Raza A, Fang Q, Ather JL, Poynter ME, Boyson JE, Bunn JY, Teuscher C. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3491-3496. doi: 10.1073/pnas.1620889114. Epub 2017 Feb 27.

Uricase Inhibits Nitrogen Dioxide-Promoted Allergic Sensitization to Inhaled Ovalbumin Independent of Uric Acid Catabolism. Ather JL, Burgess EJ, Hoyt LR, Randall MJ, Mandal MK, Matthews DE, Boyson JE, Poynter ME.
J Immunol. 2016 Sep 1;197(5):1720-32. doi: 10.4049/jimmunol.1600336. Epub 2016 Jul 27.

Scheuplein F, Lamont DJ, Poynter ME, Boyson JE, et al.  Mouse Invariant Monoclonal Antibody NKT14: A Novel Tool to Manipulate iNKT Cell Function In Vivo.  PLoS One.  2015 Oct 16;10(10):e0140729.  doi: 10.1371/ journal.pone.0140729.  eCollection 2015.  PMID: 26474487.  PMCID: PMC4608835

Benoit, P, Sigounas VY, Thompson JL, van Rooijen N, Poynter ME, Wargo MJ, Boyson JE.  The role of CD1d-restricted NKT cells in the clearance of Pseudomonas aeruginosa from the lung is dependent on the host genetic background.  Infect Immun.  2015 Jun;83(6):2557-65.  doi: 10.1128/IAI.00015-15.  Epub 2015 Apr 13.  PMID: 25870224.  PMCID: PMC4432766

Ather JL, Foley KL, Suratt BT, Boyson JE, Poynter ME.  Airway epithelial NF-kB activation promotes the ability to overcome inhalational antigen tolerance.  Clin Exp Allergy.  2015 Jul;45(7):1245-58.  doi: 10.1111/cea.12491.  PMID: 25616105.  PMCID: PMC4472492

Borg ZD, Benoit PJ, Lilley GW, Aktan I, Chant A, DeVault VL, Rincon M, Boyson JE. Polymorphisms in the CD1d promoter that regulate CD1d gene expression are associated with impaired NKT cell development.   J Immunol.  2014 Jan 1;192(1):189-99.  doi: 10.4049/jimmunol.1301451.  Epub 2013 Dec 4.  PMID: 24307737.  PMCID: PMC3903119

Klaus JP, Eisenhauer P, Russo J, Mason AB, Do D, King B, Taatjes D, Cornillez-Ty C, Boyson JE, et al.  The intracellular cargo receptor ERGIC-53 is required for the production of infectious arenavirus, coronavirus, and filovirus particles.  Cell Host Microbe.  2013 Nov 13;14(5):522-34.  doi: 10.1016/j.chom.2013.10.010.  PMID: 24237698.  PMCID: PMC3999090

Liu W, Moussawi M, Roberts B, Boyson JE, Huber SA.  Cross-regulation of T regulatory cell response after coxsackievirus B3 infection by NKT and ?o T cells in the mouse.  Am J Pathol.  2013 Aug;183(2):441-9.   doi: 10.1016/j.ajpath.2013.04.015. Epub 2013 Jun 5.  PMID: 23746656.  PMCID: PMC3730787


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