Education

1986-1990 Cornell University, Ithaca, NY; B.A. in physics; Minor in biochemistry

1990-1994 Cornell University Medical College, New York, NY; M.D.

Academic Appointments

Associate Professor, Dept. of Medicine, University ofVermont, College of Medicine

Adjunct Faculty, Dept of Microbiology and Molecular Genetics, University of Vermont, College of Agricultural and Life Sciences
Adjunct Faculty, Cell and Molecular Biology, University of Vermont

Awards and Honors

1993 Alpha Omega Alpha Medical Honor Society; Cornell University Medical College

1999 Young Investigator Award; American Society of Tropical Medicine and Hygiene

2001 Postdoctoral Fellowship for Physicians; Howard Hughes Medical Institute

2007 Young Investigator Award; American Society for Clinical Investigation

2011 Junior Researcher of the Year; University of Vermont Medical Group; University of Vermont College of Medicine

Publications

Sateriale A, Vaithilingam A, Donnelly L, Miller P, Huston CD. Feed forward regulation of phagocytosis by Entamoeba histolytica.  Infection and Immunity  2012.  80:4456-4462.  PMID: 23045476

Jumani RS, Donnelly L, Huston CD. A real time PCR assay to monitor Cryptosporidium parvum sexual stage development. Journal of Infectious Diseases.; 2015.

Roncolato EC, Teixeira JE, Barbosa JE, Zambelli Ramalho LN, Huston CD.Immunization with the Entamoeba histolytica surface proteinase EhMSP-1 protects hamsters from amebic liver abscess.  Infection and Immunity.  2015.  83:713-20.;PMID:25452550

Huston CD, Wells TNC, Spangenberg T, Burrows J, Willis P, van Voorhis W.  A proposed target product profile and developmental cascade for new cryptosporidiosis treatments.PLoS Neglected Tropical Diseases.  2015.  9(10):e0003987.doi: 10.1371/journal.pntd.0003987  PMID:  26447884.

A......Christopher Huston, MD ......Z  (multi-site study)

Open-source drug discovery with the Malaria Box compound collection for neglecteddiseases and beyond. Science.  2015.Submitted (under review).

Sateriale A, Miller P, Huston CD. Cell killing functions as the rate limiting step in host cell phagocytosis by Entamoeba histolytica  Infection and Immunity.;2015.

Bessoff K, Sateriale A, Lee KK, Huston CD.  Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth.  Antimicrobial Agents and Chemotherapy.2013. 57:1804-14.  PMID:  23380723.[Featured in the Nature Chemical Biology Research Highlights section in May, 2013

Sateriale A, Bessoff K, Sarkar IN, Huston CD.Drug repurposing:mining protozoan proteomes for known bioactive compounds.Journal of the American Medical Informatics Association.21:238-44.  PMID: 23757409

Sateriale A, Roy N, Huston CD.; SNAP-tag technology optimized for use in Entamoeba histolytica.  PLoS ONE.  2013.  : e83997. doi:10.1371/journal.pone.0083997

Vaithilingam A, Teixeira JE, Miller PJ, Heron BT, Huston CD.  Entamoeba histolytica cell surface calreticulin binds human C1q and functions in amebic phagocytosis of host cells.  Infection and Immunity.  2012.  80:2008-2018.  PMID: 22473608

Archana Vaithillingham Jose Teixeria, Peter Miller, Bradley Heron, Christopher Huston. Cellular Microbiology: Pathogen-host cell molecular Interactions: entamoebahistolytica Cell Surface Calriticulin binds Human C1Q and functions in Amebic Phagocytosis of host cells. Infect. Immun. June 2012

Jose Teixeira, Adam Sateriale, Koval Bessof and Christopher Huston, MD.Fungal and parasitic Infections:
Control of entamoeba histolytica Adherence involves Metallosurface Protease 1, and M8 Family Surface Metalloprotease withHomology to Leishmanolysin.Infect. inImmunity. 2012 80:2165-2176

Teixeira JE, Huston CD.  Evidence of a continuous endoplasmic reticulum in the protozoan parasite Entamoeba histolytica.  Eukaryotic Cell.  2008.  7:1222-1226.

Teixeira JE, Huston CD.  Participation of the serine-rich Entamoeba histolytica protein in amebic phagocytosis of apoptotic host cells.  Infection and Immunity.  2008.  76:959-966

Grace C, Alston WK, Ramundo M, Polish L, Kirkpatrick B, Huston C.  The complexity, relative value and financial worth of curbside consultations in an academic infectious diseases unit. Clinical Infectious Diseases. 2010. 51:651-5. PMID: 20687842

For more publications see pubmed link