Cardiovascular pharmacology and physiology; the contractile mechanism of cerebral arteries (ion channels and intracellular signaling), cerebral vasospasm following subarachnoid hemorrhage.
1998 B.S., University of Shizuoka, School of Pharmaceutical Science, Shizuoka, Japan
2000 M.S., Pharmacology, University of Shizuoka, Graduate School of Pharmaceutical Science, Shizuoka, Japan
2005 Ph.D., Pharmacology, University of Shizuoka, Graduate School of Pharmaceutical Science, Shizuoka, Japan
2005 Ph.D., Medicine, University of Hamamatsu School of Medicine, Hamamatsu, Japan
2015 to present Research Assistant Professor, Department of Pharmacology, University of Vermont
2010 - 2015 Research Associate, Department of Pharmacology, University of Vermont
2005 - 2010 Postdoctoral Associate, Department of Pharmacology, University of Vermont
07/01/2014 - 06/30/2018 American Heart Association, National Center, Scientist Development Grant (14SDG20150027). Mechanisms of EGF receptor activation leading to decreasing cerebral blood flow after subarachnoid hemorrhage. Role: PI
2012 Award Finalist of Next Big Idea, 11th International Conference on Neurovascular Events after Subarachnoid Hemorrhage. "Subarachnoid blood converts neutrally-evoked vasodilation to vasoconstriction in rat brain cortex"
2012 Award Finalist of Young Investigator, 11th International Conference on Neurovascular Events after Subarachnoid Hemorrhage. "Subarachnoid blood converts neutrally-evoked vasodilation to vasoconstriction in rat brain cortex"
2011, April 25 Invited Speaker, "Microvascular constriction and Ca2+ signaling after subarachnoid hemorrhage", University of Shizuoka, Shziuoka, Japan
2002 The 75th Annual Meeting Best Presentation Prize, The Japanese Pharmacological Society
For a complete list of Masayo Koide's publications, please visit PubMed.
2021 Koide M, Harraz OF, Dabertrand F, Longden TA, Ferris HR, Wellman GC, Hill-Eubanks DC, Greenstein AS, Nelson MT. Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease. J Clin Invest. 2021 Sep 15; 131(18): e149029. doi: 10.1172/JCI149029. PMID: 34351870, PMCID: PMC8439604
2021 Koide M, Ferris HR, Nelson MT, Wellman GC. Impaired Cerebral Autoregulation After Subarachnoid Hemorrhage; A Quantitative Assessment Using a Mouse Model. Front Physiol. 2021 Jun 8; 12: 688468. doi: 10.3389/fphys.2021.688468. PMID: 34168571, PMCID: PMC8218876
2021 Dabertrand F, Harraz OF, Koide M, Longden TA, Rosehart AC, Hill-Eubanks DC, Joutel A, Nelson MT. PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity. Proc Natl Acad Sci USA. 2021 Apr 27; 118(17); 32025998118. doi: 10.1073/pnas.2025998118. PMID: 33875602, PMCID: PMC8092380
2019 Sasase T, Fatchiyah F, Miyajima K, Koide M. Animal Models of Diabetes and Related Metabolic Diseases. Int J Endocrinol. 2019 Jan 6; 2019: 6147321. doi: 1155/2019/6147321. PMID: 30723499, PMCID: PMC6339747
2019 Syed AU, Koide M, Brayden JE, Wellman GC. Tonic regulation of middle meningeal artery diameter by ATP-sensitive potassium channels. J Cereb Blood Flow Metab. 2019 Apr; 39(4): 670-679. doi: 10.1177/0271678X17749392. PMID: 29260608, PMCID: PMC6446425
2018 Koide M, Moshkforoush A, Tsoukias NM, Hill-Eubanks DC, Wellman GC, Nelson MT, Dabertrand F. The yin and yang of Kv channels in cerebral small vessel disease. Microcirculation. 2018 Jan ; 25(1): 10.1111/MICC.12436. doi: 10.1111/micc.12436. PMID: 29247493, PMCID: PMC5760473
2017 Wang F, Koide M, Wellman GC. Nifedipine Inhibition of High-Voltage Activated Calcium Channel Currents in Cerebral Artery Myocytes Is Influenced by Extracellular Divalent Cations. Front Physiol. 2017 Apr 7; 8: 210. doi: 10.3389/fphys.2017.00210. eCollection 2017. PMID: 28439241; PMCID: PMC5383720
2017 Longden TA, Dabertrand F, Koide M, Gonzales AL, Tykocki NR, Brayden JE, Hill-Eubanks D, Nelson MT. Capillary K+ sensing initiates retrograde hyperpolarization to increase local cerebral blood flow. Nat Neurosci. 2017 May; 20(5): 717-726. doi: 10.1038/nn.4533. PMID: 28319610, PMCID: PMC5404963
2017 Balbi M, Koide M, Wellman CG, Plesnila N. Inversion of neurovascular coupling after subarchnoid hemorrhage in vivo. J Cereb Blood Flow Metab. 2017 Nov; 37(11): 3625-3634. doi: 10.1177/0271678X16686595. PMID: 28112024, PMCID: PMC5669344
2017 Balbi M, Koide M, Schwarzmaier SM, Wellman GC, Plesnila N. Acute changes in neurovascular reactivity after subarachnoid hemorrhage in vivo. J Cereb Blood Flow Metab. 2017 Jan; 37(1): 178-187. doi: 10.1177/0271678X15621253. PMID: 26676226