George Wellman, Ph.D.

George Wellman, Ph.D.

Professor
Department of Pharmacology

Contact Information
E-mail: George.Wellman@uvm.edu
Phone:
(802)656-3470
Office Location:
Health Sci Rsrch Facility, Rm 430

Website

Lab

Education

1986 B.S. Biology (with honors), University of Vermont, Burlington, VT

1990 M.S. Pharmacology, University of Vermont, College of Medicine

1995 Ph.D. Pharmacology, University of Vermont, College of Medicine

Awards and Honors

2006  Symposium of Biomedical Research Excellence Travel Award, National Institutional Development Award (IDeA)

2003  Visiting Professor, Center for Perinatal Biology, Loma Linda University, School of edicine, Loma Linda, CA

2000-2003  Scientist Development Grant, American Heart Association

1998 - 1999  National Research Service Award, Individual Post-doctoral Fellowship, National Institute of Health

1997  Affiliate Travel Grant Award, The Physiological Society

1995  Young Investigator Travel Award, American Heart Association

1987-1990  Graduate Teaching Fellowship, NIH

1986  B.S with honors

Teaching Experience

1998-present  Lecturer, Molecular and Cellular Pharmacology PHRM 290; topics: sodium and potassium channels, calcium signaling and regulation

2004-present Lecturer, Cardiovascular-Respiratory-Renal Course: Second year medical students: ~100 students; topics presented: drugs that alter cardiac performance, vasodilators, cardiovascular pharmacology of the sympathetic nervous system, antiarrhythmics

2004-present Pharmacological Techniques/ Research, for undergraduate and graduate students under multiple course numbers

2006-present Lecturer, Medical Pharmacology PHRM 301, topics: adrenergic pharmacology and cardiovascular pharmacology

2006-present Lecturer, Introduction to Pharmacology PHRM 201, ~50 undergraduate students, topics:  Antihypertensives, Drugs to Treat Heart Disease, Antianginal Drugs

2006-present  Lecturer, Human Physiology and Pharmacology, MPBP 301/302, ~30 graduate students, topics:  Smooth Muscle Electro-Mechanical Coupling, Structure and Function of the Autonomic Nervous System, Cholinergic and Adrenergic Receptor Pharmacology, Treatment Modalities for Arrhythmias, Vascular Physiology and Pharmacology, Renal Physiology, Pharmacology and related special topics

2009-present Director, Readings in Pharmacology PHRM 373

2009-present Lecturer, Toxicology PHRM 272, ~70 undergraduate/graduate students, topics:  poisonous animals and venomous animals

2011-present  Neural Sciences - College of Medicine Vermont Integrated Curriculum, Team-based learning session for ~ 100 first year medical students, topic:  Pharmacodynamics in Action.

2016-present, Lecturer, Foundations of Clinical Sciences, College of Medicine Vermont Integrated Curriculum, ~100 first year medical students, topics:  Sympathetic Nervous System Physiology and Pharmacology and Electronic Laboratory on Adrenergic and Cholinergic Drugs

2016-present Lecturer, Medical Cannabis PHRM 200, ~60-100 undergraduate/graduate students, topic:  Cannabis and the Cardiovascular System

Publications

For a complete list of George Wellman's publications, please visit PubMed.   Goggle Scholar Citations profile George C. Wellman

2021 Koide M, Harraz OF, Dabertrand F, Longden TA, Ferris HR, Wellman GC, Hill-Eubanks DC, Greenstein AS, Nelson MT. Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease.  J Clin Invest. 2021 Sep 15; 131(18): e149029.  doi:  10.1172/JC149029.  PMID:  34351870, PMCID:  PMC8439604

2021 Koide M, Ferris HR, Nelson MT, Wellman GC.  Impaired Cerebral Autoregulation After Subarachnoid Hemorrhage:  A Quantitative Assessment Using a Mouse Model.  Front Physiol.  2021 Jun 8; 12: 688468.  doi:  10.3389/fphys.2021.688468.  PMID:  34168571, PMCID:  PMC8218876

2021 Wang F, Luo MY, Zhou L, Yang L, Lanzino G, Chang HJ, Wellman GC.  Endocrine Dysfunction Following Stroke.  J Neuroimmune Pharmacol. 2021 Jun; 16(2): 425-436.  doi:  10.1007/s11481-020-09935-6.  PMID:  32621001

2019 Syed Au, Koid M, Brayden JE, Wellman GC.  Tonic regulation of middle meningeal artery diameter by ATP sensitive potassium channels.  J Cereb Blood Flow Metab.  2019 Apr; 39(4):  670-679.  doi:  10.1177/0271678X17749392.  PMID:  29260608, PMCID:  PMC6446425

2018 Koide M, Moshkforoush A, Tsoukias NM, Hill-Eubanks DC, Wellman GC, Nelson MT, Dabertrand F.  The yin and yang of Kv channels in cerebral small vessel pathologies.  Microcirculation.  2018 Jan; 25(1).  doi:  10.1111/micc.12436.  PMID:  29247493, PMCID:  PMC5760473

2017 Wang F, Koide M, Wellman GC.  Nifedipine Inhibition of High-Voltage Activated Calcium Channel Currents in Cerebral Artery Myocytes is Influenced by Extracellular Divalent Cations, Front Physiol.  2017 Apr 7;  8:  210.  doi:  10.3389/fphys.2017.00210.  PMID:  28439241, PMCID:  PMC5383720

2017 Balbi M, Koide M, Wellman GC, Plesnila N.  Inversion of neurovascular coupling after subarachnoid hemorrhage in vivo.  J Cereb Blood Flow Metab.  2017 Jan 1. doi:  10.1177/0271678X16686596.  PMID:  28112024

2017 Villalba N, Sackheim AM, Nunez IA, Hill-Eubanks DC, Nelson MT, Wellman GC, Freeman K.  Traumatic Brain Injury Causes Endothelial Dysfunction in the Systemic Microcirculation through Arginase-1-Dependent Uncoupling of Endothelial Nitric Oxide Synthase.  J Neurotrauma.  2017 Jan1;  34(1):  192-203.  doi:  10.1089/neu.2015.4340.  PMID:  26757855, PMCID:  PMC5198065.  Journal Cover.

2017 Balbi M, Koide M, Schwarzmaier SM, Wellman GC, Plesnila N.  Acute changes in neurovascular reactivity after subarachnoid hemorrhage in vivo.  J Cereb Blood Flow Metab.  2017 Jan;  37(1):  178-187.  PMID:  26676226, PMCID:  PMC5363735

2016 Pappas AC, Koide M, Wellman GC.  Purinergic signaling triggers endfoot high--amplitude Ca2+ signals and causes inversion of neurovascular coupling after subarachnoid hemorrhage.  J Cereb Blood Flow Metab.  2016 Nov;  36(11):  1901-1912.  PMID:  27207166, PMCID:  PMC5094310