Karen M. Lounsbury, Ph.D.

Karen M. Lounsbury, Ph.D.

Professor
Department of Pharmacology

Contact Information
E-mail: Karen.Lounsbury@uvm.edu
Phone:
(802)656-1319
Office Location:
Health Sci Rsrch Facility, Rm 320

Website

Lab

Education

1980-1983 Easton Area High School, Easton, PA

1983-1987 B.S. Biochemistry; The Pennsylvania State University, University Park, PAResearch Mentor: Dr. Richard Bernlohr, Ph.D.

1987-1993 Ph.D. Pharmacology; Department of PharmacologyThe University of Pennsylvania, Philadelphia, PADissertation Advisor: Dr. David Manning, Ph.D.

1993-1996 Post-doctoral Fellow; Department of Pathology and Vermont Cancer Center, The niversity of Vermont, Burlington, VT. Supervisor: Dr. Ian Macara, Ph.D.

1996-1997 Post-doctoral Associate; Department of PharmacologyThe University of Vermont, Burlington, VTSupervisor: Dr. Mark Nelson, Ph.D. and Dr. Joseph Brayden, Ph.D.

Research Interests

Signal Transduction in Vascular Remodeling: Signaling through transcription factors during normal or pathological cell growth; tumor angiogenesis; hypertension and atherosclerosis; regulation by calcium, growth factors and hypoxia/ischemia; control of timed cell division; nuclear transport kinetics; subcellular imaging of signaling molecules; manipulation of recombinant protein structure/function.

Academic Appointments

1999 - Present Cell and Molecular Biology Faculty; University of Vermont, Burlington, VT

1998 - Present Member Vermont Cancer Center; University of Vermont, Burlington, VT

1998 - 2004 Assistant Professor of Pharmacology, University of Vermont, Burlington, VT

2010 - Present Professor of Pharmacology, University of Vermont, Burlington, VT

2004 - 2010 Associate Professor of Pharmacology, University of Vermont, Burlington, VT

2017  Director of Medical Masters Program

Awards and Honors

2016 Nominated for the Kroepsch-Maurice Excellence in Teaching Award

Teaching Experience

2016, 2017 Co-Director and Lecturer, Medical Cannabis PHRM 200.

2016, 2017  Developer and Lecturer, Cannabis Science Online:  Webinar on Cannabis Pharmcology (1 hr.), Certificate Program (2 hr.)  Continuing Medical Education Modules on Pharmacology and Motor Disorders (2 hr.)

2015-2017  Director and Lecturer, Medical Pharmacology, PHRM 301

2006-2017 Designer, Director, Lecturer, Introduction to Pharmacology PHRM 201

2010-2016  Developer, Director, Facilitator, Milestones in Pharmacology

2004-2017  Lecturer and Small Group Facilitator, Vermont Integrated Curriculum (110 medical students) Topics include:  Neural Sciences, Attacks and Defenses, Adverse Drug Reactions, NMGI, Drug Interactions,

1999-2017  Lecturer, Topics in Molecular Pharmacology PHRM 290 - Signal Transduction

2007-2017  Lecturer, Toxicology PHRM 272, Toxicology of Particulates, Alcohol and Ethanol, and Cigarette Smoking

Currently Teaching Lectures for Pathology 305 (Angiogenesis), Biochemistry 272 (Angiogenesis), VIC Foundations of Medicine (Pharmacodynamics), VIC Human Structure and Function (Parmacokinetics).  Also, co-developed and instructed a team-based learning module for VIC Neural Sciences Pharmacology:  Migraines.

Publications

For a complete list of Karen M. Lounsbury's publications, please visit PubMed.
For Goggle Scholar citation profile, please visit Karen M. Lounsbury

2021 Finnie SM, Brach RJ, Dawson CA, Epstein SB, Goyal RK, Lounsbury KM, Eldakar-Hein ST, Lahey T.  A new roadmap for social medicine curriculum design based on mixed methods student and faculty evaluations of the preclinical curriculum.  BMC Med Educ.  2021 Aug 20; 21(1):  442.  doi:  10.1186/s12909-021-02885-4.  PMID:  34416885, PMCID:  PMC7949242

2021 Goyal RK, Dawson CA, Epstein SB, Brach RJ, Finnie SM, Lounsbury KM, Lahey T, Eldakar-Hein ST.  Correction to:  the design and implementation of a longitudinal social medicine curriculum at the University of Vermont, Larner College of Medicine.  BMC Med Educ. 2021 Mar 10; 21(1):  154. doi:  10.1186/s12909-021-02594-y.  PMID:  33691675, PMCID:  PMC7949242

2021 Goyal RK, Dawson CA, Epstein SB, Brach RJ, Finnie SM, Lounsbury KM, Lahey T, Eldakar-Hein ST. The design and implementation of a longitudinal social medicine curriculum at the University of Vermont's Larner College of Medicine.  BMC Med Educ.  2021 Feb 24; 21(1):  131.  doi:  10.1186/s12909-021-02533-x.  PMID   33627097, PMCID:  PMC7903930

2018 Suarez-Martinez AD, Peirce SM, Isakson BE, Nice M, Wang J, Lounsbury KM, Scallan JP, Murfee WL. Induction of microvascular network growth in the mouse mesentery.  Microcirculation.  2018 Nov; 25(8): e12502.  doi:  10.1111/micc.12502.  PMID:  30178505, PMCID:  PMC7446122

2017  Mirando AC, Abdi K, Wo P, Lounsbury KM.  Assessing the effects of threonyl-tRNA synthetase on angiogenesis-related responses.  Methods.  2017 Jan 15;  113:  132-138.  doi:  10.1016/j.ymeth.2016.11.007.  PMID:  27847344, PMCID:  5292763

2016  Lounsbury KM, Francklyn CS.  Aminoacyl-Transfer RNA Synthetases:  Connecting Nutrient Status to Angiogenesis Through the Unfolded Protein Response.  Arterioscler Thromb Vasc Biol.  2016 Apr;  36(4):  582-583.  doi:  10.1161/ATVBAHA.116.307193.  PMID:  27010025,  PMCID:  PMC4807867

2015 Mirando AC, Fang P, Williams TF, Baldor LC, Howe AK, Ebert AM, Wilkinson B, Lounsbury KM, Guo M, Francklyn CS.  Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor.  Sci Rep.  2015 Aug 14;  5:  13160.  PMID:  26271225, PMCID:  PMC4536658

2015  Mirando AC, Francklyn CS, Lounsbury KM.  Regulation of angiogenesis by aminoacyl-tRNA synthetases.  Int J Mol Sci.  doi:  10.3390/ijms151223725.  PMID:  25535072, PMCID:  PMC4284789