Benedek Erdos

Benedek Erdos

Contact Information
E-mail: Benedek.Erdos@uvm.edu
Phone:
802-656-0988
Office Location:
89 Beaumont Ave, Given E315A, Burlington, VT 05405

Education

1999-2004  Ph.D.  Semmelweis University, School of Medicine, Budapest, Hungary
1993-1999  M.D.   Semmelweis University, School of Medicine, Budapest, Hungary

Awards and Honors

Inaugural Bloomfield Endowed Professorship - Cardiovascular Research Institute of Vermont 2017-2019

Professional Positions

2014-Present  Assistant Professor, Department of Pharmacology, University of Vermont

2011-2014  Research Assistant Professor, Department of Physiology and Functional Genomics, University of Florida, College of Medicine, Gainesville, FL

2008-2011  Research Assistant Professor, Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Gainesville, FL

2006-2008  Assistant Instructor, Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Gainesville, FL

2005-2011  Research Coordinator,  Hypertension and Aging Laboratory, Malcom Randall VA Medical Center, Gainesville, FL

2004-2006  Postdoctoral Associate, Department of Pharmacology and Therapeutics, University of Florida, College of Medicine, Gainesville, FL

2001-2004  Postdoctoral Associate, Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, NC

1994-2001  Research Assistance, Institute of Human Physiology and Clinical Experimental Research, Semmelweis University, Budapest, Hungary

Research Grants

2016-2021  NIH/NHLBI  R01   "Brain--derived neurotrophic factor:  a novel regulator of cardiovascular function in the hypothalamus", PI:  B. Erdos

American Heart Association, 7/1/2011 - 6/30/2015, Scientist Development Grant  "Hydrogen peroxide and age-related sympathetic nervous system dysregulation"

American Federation for Aging Research,  07/1/2011 - 06/30/2013, "Hydrogen peroxide and age-related sympathetic nervous system dysregulation", pursuing one aim: to determine whether caloric restriction prevents age-related sympathetic nervous system dysregulation by maintaining adequate catalase expression, low hydrogen peroxide levels and normal catecholaminergic neurotransmission in the hypothalamus and brainstem.

Presentations

2012  Invited Speaker  Burnett School of Biomedical Sciences, University of Central Florida

2012  Invited Speaker  Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida

2012  Invited Speaker  Department of Physiological Sciences, College of Veterinary Medicine, University of Florida

2010  Invited Speaker  Department of Food Science and Human Nutrition, University of Florida

2010  Invited Speaker  Geriatric Research, Education, and Clinical Center at Gainesville, FL

2009  Invited Speaker  Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL

2007  Invited Speaker  Department of Physiology, Medical College of Georgia, Augusta, GA

2007  Invited Speaker  Institute on Aging and GRECC seminar series,  University of Florida, Gainesville, FL

2006  Invited Speaker  Microcirculatory Society, Young Investigator Symposium, Experimental Biology, San Francisco, CA

Professional Activities

Professional Memberships:
    American Journal of Physiology Society
    American Heart Association

Journal Referee:
    American Journal of Physiology - Heart and Circulatory Physiology
    British Journal of Pharmacology
    Circulation
    Diabetes
    Experimental Physiology
    Frontiers in Physiology
    International Journal of Developmental Neuroscience
    Journal of the Renin-Angiotensin-Aldosterone System
    Kidney International
    Letters in Drug Design & Discovery

Grant Study Section:
    American Heart Association - Greater Southeast Affiliate, Vascular Biology & Blood Pressure Study
    Group (2009 - present)

Publications (Peer Reviewed)

For a complete listing of publications go to PubMed.

2021 Thorsdottir D, Einwag Z, Erdos B.  BDNF shifts excitatory-inhibitory balance in the paraventricular nucleus of the hypothalamus to elevate blood pressure.  J Neurophysiol.  2021 Oct 1; 126(4): 129-1220.  doi: 10.1152/jn.00247.2021.  PMID:  34406887

2019 Thorsdottir D, Cruickshank NC, Einwag Z, Hennig GW, Erdos B.  BDNF downregulates ß-adrenergic receptor-mediated hypotensive mechanisms in the paraventricular nucleus of the hypothalamus.  Am J Physiol Heart Circ Physiol.  2019 Dec 1; 317(6):  H1258-H1771.  doi:  10.1152/ajpheart.00478.2019.  PMID:  31603352, PMCID:  PMC6962618

2018 Schaich CL, Wellman TL, Einwag Z, Dutko RA, Erdos B.  Inhibition of BDNF signaling in the paraventricular nucleus of the hypothalamus lowers acute stress-induced pressor responses.  J Neurophysiol. 2018 Aug 1; 120(2): 633-643. doi:  10.1152/jn.00459.207.  PMID:  29694277, PMCID:  PMC6139453

2017  Basgut B, Whidden MA, Kirichenko N, Woods M, Erdos B, Scarpace PJ, Tumer N.  Effect of High-Salt on Age-Related High Blood Pressure and Hypothalamic Redox Signaling.  Pharmacology.  2017 May 19;  100(3-4):  105-114.  doi:  10.1159/000472259.  PMID:  28521325

2016  Whidden MA, Basgut B, Kirichenko N, Erdos B, Tumer N.  Altered potassium ATP channel signaling in mesenteric arteries of old high salt-fed rats.  J Exerc Nutrition Biochem.  2016 Jun;  20(2):  58-64.  doi:  10.20463/jenb.2016.06.20.2.8.  PMID:  27508155, PMCID:  PMC4977904

2016  Gocmez SS, Scarpace PJ, Whidden MA, Erdos B, Kirichenko N, Sakarya Y, Utkan T, Tumer N.  Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries.  J Exerc Nutrition Biochem.  2016 Mar 31;  20(1):  41-48.  doi:  10.20463/jenb.2016.03.20.1.2.  PMID:  27298812, PMCID:  PMC4899900

2016  Schaich CL, Wellman TL, Koi B, Erdos B.  BDNF acting in the hypothalamus induces acute pressor responses under permissive control of angiotensin II.  Auton Neurosci.  2016 May ;  197:  1-8.  doi:  10.1016/j.autneu.2016.02.011.  PMID:  26948539

2015  Erdos B, Clifton RR, Liu M, Li H, McCowan ML, Sumners C, Scheuer DA.  Novel mechanism within the paraventricular nucleus reduces both blood pressure and hypothalamic pituitary-adrenal axis responses to acute stress.  Am J Physiol Heart Circ Physiol.  doi: 10.1152/ajpheart.00207.2015.  PMID:  26071542, PMCID:  PMC4537949

2015  Erdos B, Backes I, McGowan ML, Hayward LF, Scheuer DA.  Brain-derived neurotrophic factor modulates angiotensin signaling in the hypothalamus to increase blood pressure in rats.  Am J Physiol Heart Circ Physiol.  doi:  10.1152/ajpheart.00776.2014.  PMID:  25576628, PMCID:  PMC4360054